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Name: Dr. Salman Khan
Designation: Assistant Professor
Department: Pharmacy


Qualifications: PhD (SNU, South Korea), Post Doc (SNU, South Korea), Post Doc (McGill Univ., Canada)


Phone: +92-51 9064-4056
Email: skhan@qau.edu.pk
Status: On Job
Other Weblink: https://scholar.google.com.pk/citations?hl=en&user=dfYfFCgAAAAJ&view_op=list_works&sortby=pubdate


Research Interests Publications Conferences Research Projects

Neuropharmacology & Analgesia, Immuno-Molecular Pharmacology, Biochemical-Systemic Pharmacology

Salman Khan; Omer Shehzad; Hussain Ali; Yeong Shik Kim (2016), Nitric oxide signaling is a therapeutic strategy and a compensatory mechanism for neuroprotective and anti-neuroinflammatory properties of capillarisin, (Plos One-Submission ID: PONE-D-16-32096).

YS Kim, Salman Khan. Molecular approach toward instantaneous molecular cascades and great understanding of neuroinflammation and neuropathy (2016). (Frontiers in Pharmacology-Neuropharmacology: Submission ID: 219079) 

Salman Khan, RJ Choi, JH Lee, YS Kim. Attenuation of neuropathic pain and neuroinflammatory responses by a pyranocoumarin derivative in animal and cellular models. (European Journal of Pharmacology 774 (2016), 95–104).)

Salman Khan, O Shehzad, R Li, MS Cheng, and YS Kim. Pharmacological mechanism underlying anti-inflammatory properties of two structurally divergent coumarins through inhibition of pro-inflammatory enzymes and cytokines. (Journal of Inflammation (2015)29; 12:47).

Salman Khan, O. Shehzad, J. Chun, R, J. Choi, M. N. Islam, J. S. Choi, and Y. S. Kim. Anti-hyperalgesic and anti-allodynic activities of capillarisin via suppression of inflammatory signaling in animal model. (J Ethnopharmacol. 2014, 28; 152(3):478-86).

Salman Khan, O. Shehzad, K. J. Lee, A. Tosun, Y. S. Kim. Anti-inflammatory properties of samidin from Sesli resinosm though suppression of NF-κB and AP-1-mediated-genes in LPS-stimulated RAW 264.7 cells. (Archive of Pharmacal Research (2014), 37(11):1496-503.

R. J Choi, J. Chun, Salman Khan and Y. S. Kim. Desoxyrhapontigenin, a potent anti-inflammatory phytochemical, inhibits LPS-induced inflammatory responses via suppressing NF-κB and MAPK pathways in RAW 264.7 cells. International Immunopharmacology 18 (2014) 182–190).

A Tosun, Salman Khan, YS Kim, á Calín-Sánchez, X Hysenaj and Aá Carbonell-Barrachina. Essential Oil Composition and Anti-Inflammatory Activity of Salvia officinalis L (Lamiaceae) in Murin Macrophages. Tropical Journal of Pharmaceutical Research (2014); 13 (6): 937-942.

Salman Khan, O. Shehzad, J. Chun, Y. S. Kim. Mechanism underlying anti-hyperalgesic and anti-allodynic properties of anomalin in both acute and chronic inflammatory pain models in mice through inhibition of NF-κB, MAPKs and CREB signaling cascades. European Journal of Pharmacology 718 (2013) 448–458.

Salman Khan, R. J. Choi, O. Shehzad, H. P. Kim, M. N. Islam, J. S. Choi, and Y. S. Kim. Molecular mechanism of capillarisin-mediated inhibition of MyD88/TIRAP inflammatory signals in in vitro and in vivo experimental models. Journal of Ethnopharmacology 145 (2013) 626–637.

Salman Khan and Y. S. Kim. Molecular mechanism of inflammatory signaling and predominant role of Saposhnikovia divaricata as anti-inflammatory potential. Natural Product Sciences 19(2): 1-7 (2013).

O. Shehzad, Salman Khan, I.J.  Ha, Y. Park, A. Tosun, Y. S. Kim. Application of stepwise gradients in counter-current chromatography: A rapid and economical strategy for the one-step separation of eight coumarins from Seseli resinosum. Journal of Chromatography A, 1310 (2013) 66–73.

Salman Khan, A. Shehzad, O. Shehzad, and E. A Al-Suhaimi. Inpatient antibiotics pharmacology and physiological use in Hayatabad Medical Complex, Pakistan. International Journal of Physiology, Pathophysiology and Pharmacology, 2013; 5(2):120-127.

R. J. Choi, T. M. Ngoc, K. Bae, H. J. Cho , D. D. Kim, J. Chun, Salman Khan, Y. S. Kim. Anti-inflammatory properties of anthraquinones and their relationship with the regulation of P-glycoprotein function and expression. European Journal of Pharmaceutical Sciences 48 (2013) 272–281.

Salman Khan, O. Shehzad, E. R. Woo, S. S. Kang, S. W. Baek, J. Kim, Y. S. Kim. Anti-inflammatory Mechanism of 15,16-Epoxy-3α-hydroxylabda-8,13(16),14-trien-7-one via Inhibition of LPS-Induced Multicellular Signaling Pathways. Journal of Natural Products 2012, 75, 67−71.

J. Chun , R. J. Choi, Salman Khan, D. S. Lee, Y.C Kim, Y. J Nam,, D. U Lee, Y. S. Kim. Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-κB, MAPK and AP-1 via the MyD88 signaling pathway in LPS-activated RAW 264.7 cells. International Immunopharmacology. 2012, 14(4):375-83.

O. Shehzad, Salman Khan, I. J. Ha, Y. Park, Y. S. Kim. Rational development of a selection model for solvent gradients in single-step separation of ginsenosides from Panax ginseng using high-speed counter-current chromatography. Journal of Separation Science, 2012, 35, 1462–1469.

A. Shehzad, Salman Khan, Y. S Lee. Curcumin molecular targets in obesity and obesity related cancer. Future Oncology, 2012, 8(2), 1-12.

Salman Khan, E. M. Shin, Y. H. Jung, J. Kim, A. Tosun, Y. S. Kim. Suppression of LPS-induced inflammatory and NF-κB responses by anomalin in RAW 264.7 macrophages. Journal of Cellular Biochemistry, 2011, 112(8):2179-88.

Salman Khan, R. J. Choi, Dong-Ung Lee, Y. S. Kim. Sesquiterpenes derivatives isolated from Cyperus rotundus L. inhibits inflammatory signaling mediated by NF-κB pathway. Natural Product Sciences. 2011, 17(3): 250-255.

O. Shehzad, Salman Khan, T. Khan and JK Park.  Physicochemical and mechanical characterization of bacterial cellulose produced with an excellent productivity in static conditions using a simple fed-batch cultivation strategy. Carbohydrate Polymers 82 (2010) 173-180.

A. Shehzad, Salman Khan, O. Shehzad, and Y. S. Lee. Curcumin therapeutic promises and bioavailability in colorectal cancer. Drugs of Today, 2010, 46(7): 523.

Salman Khan, O. Shehzad, T. Khan, J.H. Ha and J. K. Park, Production of Bacterial Cellulose by Gluconacetobacter hansenii using a new bioreactor equipped with centrifugal impellers. Korean Chem. Eng. Res. (2009), 47 (4), 506-511.

J. K. Park, O. Shehzad, T. Khan, Salman Khan. Production of bacterial cellulose by G.hasenii using a new bioreactor equipped with centrifugal impellers, Journal of Biotechnology, 136S (2008) S460–S495.

T. Khan, Salman Khan, J. K. Park. Simple fed-batch cultivation strategy for the enhanced production of single-sugar glucuronic acid-based oligosaccharides by a cellulose-producing Gluconacetobacter strain. Biotechnology and Bioprocess Engineering (2008) 13, 240-247.

O. Shehzad, Salman Khan, T. Khan, and JK. Park, Production of bacterial cellulose in static conditions by a simple fed-batch cultivation strategy. Korean J. Chem. Eng., DOI: 10.2478/s11814-009-0232-5.

J. H. Ha, O. Shehzad, Salman Khan, S.Y. Lee, J. W. Park, T. Khan, J.K. Park, Production of bacterial cellulose by a static cultivation using the waste from beer culture broth, Production of bacterial cellulose by a static cultivation using the waste from beer culture broth. Korean J. Chem. Eng., 25(4), 812-815 (2008). 

BOOK CHAPTERS

Salman Khan, A. Tosun, YS Kim. Ginsenosides as Food Supplements and their Potential Role in Immunological and Neurodegenerative Disorders. Chapter 31, 10031-WATSON-9780124114623, Bioactive Nutriceuticals and Food Supplements in Neurological and Brain Disease (2015 Elsevier Inc.).

A. Tosun, Salman Khan. Antioxidant Actions of Spices and their Phytochemicals on autoimmunity. WATSON-9780124114623, Bioactive Nutriceuticals and Food Supplements in Neurological and Brain Disease (2015 Elsevier Inc.).

ORAL PRESENTATION

Salman Khan, RJ Choi, JH Lee, YS Kim. Attenuation of neuropathic pain and neuroinflammatory responses by a pyranocoumarin derivative, anomalin in animal and cellular models. Proceeding of the 46th Annual Meeting of the Korean Society of Pharmacognosy (December 03, 2015), Seoul, South Korea

Salman Khan. Potential of anti-inflammation in relieving diabetic neuropathy. 9th Annual Symposium 2014, Canadian Institute of Health Research (CIHR-Neuroinflammation Program), McGill University, Montreal, Quebec, Canada.  

Salman Khan, R. J. Choi, O. Shehzad, H. P. Kim, M. N. Islam, J. S. Choi, and Y. S. Kim. Molecular mechanism of capillarisin-mediated inhibition of MyD88/TIRAP inflammatory signaling and its anti-hyperalgesic effect in an inflammatory pain models. 11th CGCM meeting August 20~24, Macau, 2012.

Salman Khan, E. M. Shin, Y. H. Jung, J. Kim, A. Tosun, Y. Shik Kim. Anomalin, pyranocoumarin inhibits LPS-induced expression of inflammatory mediators via NF-κB and MAP-kinase signaling pathways. 10th CGCM meeting August 26~ 28, Shanghai, China, 2011.

Salman Khan, E. M. Shin, Y. H. Jung, J. Kim, Y. Shik Kim. Suppression of LPS-induced inflammatory and NF-κB responses by anomalin isolated from the root of Saphoshnikovia divaricata in RAW 264.7 macrophages. December 22-24, (Tokoshima), Japan, 2010.

Salman Khan, E. M. Shin, D-U. Lee, Y. S. Kim. Bioactivity guided evaluation of sesquiterpenes as an anti-inflammatory activity isolated from Cyperus rotundus L: Effect of chemical structures and cellular signaling pathway. 9th CGCM meeting, Hong Kong, 2010.

INTERNATIONAL ABSRACTS AND POSTER PRESENTATIONS/ CONFERENCES

Salman Khan. Potential of anti-inflammation in relieving diabetic neuropathy. Annual meeting of Neuro-inflammation, McGill University, Montreal, Canada (August 15, 2014)

Salman Khan, O. Shehzad, J. Chun, and Y. S. Kim. Mechanism underlying anti-hyperalgesic and anti-allodynic properties of anomalin in both acute and chronic inflammatory pain models in mice through inhibition of NF-κB, CREB and MAPKs signaling cascades. Korean Society of Pharamcognosy 2012. 06. (Seoul, Korea)

Salman Khan, R. J. Choi, O. Shehzad, H. P. Kim, M. N. Islam, J. S. Choi, and Y. S. Kim. Molecular mechanism of capillarisin-mediated inhibition of MyD88/TIRAP inflammatory signaling and its anti-hyperalgesic effect in an inflammatory pain models. 11th CGCM meeting August 20~24, Macau, 2012.

 Salman Khan, E. M. Shin, S. W. Baek, J. Kim, Y. S. Kim. Novel labdan diterpene derivative isolated from Leonurus japonicum as a function of anti-inflammatory activity in LPS-stimulated RAW 264.7 cells. 9th CGCM meeting Hong Kong 2010

Salman Khan, E. M. Shin, Y. H. Jung, J. Kim, Y. S. Kim. Anti-inflammatory and anti-NF-κB effects of anomalin isolated from the root of Saposhnikovia divaricata in LPS-stimulated RAW264.7 macrophages.  9th CGCM meeting Hong Kong 2010.

Salman Khan, E. M. Shin, Y. H. Jung, J. Kim, Y. Shik Kim. Suppression of LPS-induced inflammatory and NF-κB responses by anomalin isolated from the root of Saphoshnikovia divaricata in RAW 264.7 macrophages. (Tokoshima), Japan, December 22-24, 2010.

 Salman Khan, O. Shehzad, T. Khan, J. K. Park, Investigation of flow pattern and volumetric oxygen transfer coefficient (KLa) for new bioreactors equipped with centrifugal impellers. Korean Society of Biotechnology and Bioprocess engineering (KSBB), Jinju S. Korea, 2008. 

Salman Khan, O. Shehzad, T. Khan, J. K. Park, Treatment of Brewery Waste for the Improved Production of Bacterial Cellulose by a Gluconacetobacter Strain, Young Asian Biochemical Engineers’s Community 2007(YABEC), Japan

Salman Khan, O. Shehzad, T. Khan, J. K. Park, Evaluation of Autolyzed waste of beer fermentation broth as a basal medium for the production of bacterial cellulose and oligosaccharides Gluconacetobacter hansenii, Korean Institute of Chemical Engineers 2007 (KIChE-2007), Daejon, South Korea.

Salman Khan, O. Shehzad, T. Khan, J. K. Park, Production and structure feature of bacterial cellulose using nano-bubble system, Young Asian Biochemical Engineers’s Community 2008 (YABEC-2008), Japan.

Salman Khan, O. Shehzad, T. Khan, J. K. Park, Production of bacterial cellulose using waste from beer fermentation broth in shaking cultivation, Korean Society of Biotechnology and Bioprocess engineering (KSBB), Jeju do, Korea, 2008

O. Shehzad, Salman Khan, T. Khan, J. K. Park, Production of Bacterial Cellulose membrane by G. hasenii using fed batch cultivation. (Korean Society of Biotechnology and Bioprocess engineering (KSBB), Jinju S. Korea, 2008).

O. Shehzad, Salman Khan, T. Khan, J. K. Park, Production of bacterial cellulose in fed batch cultivation using waste from beer fermentation broth. Korean Institute of Chemical Engineers (KIChE-2008), Pusan, Oct 22, 2008, South Korea.

O. Shehzad, Salman Khan, T. Khan, J. K. Park, Physico-Chemico-Mechanical characteristics of bacterial cellulose produced in fed batch cultivation using waste from beer fermentation broth. Korean Institute of Chemical Engineers (KIChE-2008), Pusan, Oct 22, 2008, South Korea.

Salman Khan (PI), Gul Majid Khan (Co-PI); “Evaluation of phenolic compounds effect on streptozotocin-induced diabetes and related neuropathic pain model in mice”, 2015-2016 HEC, Pakistan (Rs. 419000) in-Progress)

 Salman Khan (Co-PI), Ji Zhang.  Potential of anti-inflammation in relieving diabetic neuropathy. Neuroinflammation Training Program, McGill University, Montreal, Quebec, Canada, April 01, 2014~ April 30, 2015. (40000USD) Completed.

 Salman Khan (PI), YS Kim (Co-PI). BK-21-plus, College of Pharmacy, Seoul National University, Seoul, South Korea, 2013~ 2014 (30000USA) Completed.

Salman Khan (PI), Hussain Ali (Co-PI). Therapeutic potential of anti-inflammation in attenuation of neurodegenerative diseases: molecular approach toward specific targets (NRPU-submitted to HEC, Pakistan)

Hussain Ali (PI), Salman Khan (Co-PI); “Preparation and characterization of drug loaded PLGA/pH- sensitive PLGA-nanoparticles for therapeutic applications”, HEC, Pakistan (Submitted)



Quaid-i-Azam University Islamabad, 45320, Pakistan.
Tel: +92-51 9064 0000, Email:webmaster@qau.edu.pk