Scientific Publications

1.      “Enantioselective Conversion of Primary Alcohols to α-Methylene γ-Butyrolactones via Iridium Catalyzed C-C Bond Forming Transfer Hydrogenation: 2-(Alkoxycarbonyl)allylation,”

Montgomery, T. P.; Hassan, A.; Park, B. Y.; Krische, M. J. J. Am. Chem. Soc. 2012 ASAP, DOI: 10.1021/ja303839h

2.      “Consecutive Iridium Catalyzed C-C and C-H Bond Forming Hydrogenations for the Diastereo- and Enantioselective Synthesis of syn-3-Fluoro-1-Alcohols: C-H (2-Fluoro)allylation of Primary Alcohols,”

Hassan, A.; Montgomery, T. P.; Krische, M. J.  Chem. Commun., 2012, 47, 4692.

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3.      “Unlocking Hydrogenation for C-C Bond Formation: A Brief Overview of Enantioselective Methods”

Hassan, A.; Krische, M. J. Org. Process Res. Dev. 2011, 15, 1236.

4.      “Catalytic Enantioselective Grignard Nozaki-Hiyama Methallylation from the Alcohol Oxidation Level: Chloride Compensates for π-Complex Instability”

Hassan, A.; Townsend, I. A.; Krische, M. J. Chem. Commun. 2011, 47, 10028.

Highlighted in Synfacts 2011, 1206.

5.      “Enantioselective Vinylogous Aldol-Reformatsky Addition from the Alcohol or Aldehyde Oxidation Level via Iridium Catalyzed Transfer Hydrogenation: Linear Regioselectivity by Way of C-Bound Iridium Enolates”

Hassan, A.; Zbieg, J. R.; Krische, M. J. Angew. Chem. Int. Ed.  2011, 50, 3493.

Highlighted in Synfacts 2011, 741.

6.      “Total Synthesis of (+)-Roxaticin: A Departure from Stoichiometric Chiral Reagents, Auxiliaries and Premetallated Nucleophiles in Polyketide Construction”

Han, S. B.; Hassan, A.; Kim, I.-S.; Krische, M. J. J. Am. Chem. Soc. 2010, 132, 15559.

Highlighted in Synfacts 2011, 121.

7.      “Elongation of 1,3-Polyols via Iterative Catalyst-Directed Carbonyl Allylation from the Alcohol Oxidation Level”

Hassan, A.; Lu, Y.; Krische, M. J. Org. Lett. 2009, 11, 3112.

8.      “1,n-Glycols as Dialdehyde Equivalent in Iridium Catalyzed Enantioselective Carbonyl Allylation form the Alcohol Oxidation Level and Iterative Two-Directional Assembly of 1,3-Polyols”

Lu, Y.; Kim, I.-S.; Hassan, A.; Del Valle, D. J.; Krische, M. J. Angew. Chem. Int. Ed. 2009, 48, 5018.

Highlighted in Synfacts 2009, 997.

9.      “Diastereo- and Enantioselective Reductive Aldol Addition of Vinyl Ketones via Catalytic Hydrogenation”

Han, S. B.; Hassan, A.; Krische, M. J. Synthesis 2008, 2669.

10.   “Diastereo- and Enantioselective Hydrogenative Aldol Coupling of Vinyl Ketones: Design of an Effective Monodentate TADDOL-Like Phosphonite Ligand”

Bee C.; Han, S. B.; Hassan, A.; Iida, H.; Krische, M. J. J. Am. Chem. Soc. 2008, 130, 2746.

Highlighted in Synfacts 2008, 596.