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Name: Dr. Mariam Anees
Designation: Assistant Professor
Department: Biochemistry (BMB)


Qualifications: Doctor of Philosophy (PhD)
Medical University of Vienna, Vienna, Austria
Jan 2008 - February 2012
Major Field: Molecular Biology
Specific Area: Cancer Therapeutics




Phone: +92-51 9064-3224
Email: mariam@qau.edu.pk
Status: On Job
Other Weblink: https://www.researchgate.net/profile/Mariam_Anees

View Resume

Research Interests Publications Conferences Research Projects

  • Interaction of signal transduction pathways and consequent effect on cancer pathogenesis.
  • Cancer Immune Surveillance with reference to the involvement/contribution of specific immune cells.
  • Testing of drugs/plant extracts for their anti-cancer activity in vitro and in vivo.
  • TNF-Related Apoptosis-Inducing Ligand (TRAIL) pathway.
1.    Tumor suppressor candidate 3 (TUSC3) prevents the epithelial-to-mesenchymal transition and inhibits tumor growth by modulating the endoplasmic reticulum stress response in ovarian cancer cells. Kratochvílová K, Horak P, Ešner M, Souček K, Pils D, Anees M, Tomasich M, Dráfi F, Jurtíková V, Hampl A, Krainer M, Vaňhara P (2015) International Journal of Cancer - In Press.

2.     Effect of Maternal Iodine Supplementation on Thyroid Function and Birth Outcome in Goiter Endemic Areas. Anees M, Anis RA, Yousaf S, Murtaza I, Sultan A, Arslan M, Shahab M (2015) Current Medical Research and Opinion – In Press.

3.    Clinical Role of HER2 gene Amplification and chromosome 17: A cohort Study on 154 Immunohistochemically-Equivocal Cases of Pakistani Invasive Breast Carcinoma Patients. Murtaza I, Anees M, Sultan A (2015) Tumor Biology – In Press.

4.       The potential evasion of immune surveillance in MALT lymphoma by DcR2-mediated upregulation of NF-ĸB. Anees M, Horak P, Schiefer AI, Perco P, Vanhara P, El-Gazzar A, Müllauer L, Streubel B, Raderer M, Krainer M (2014) Leukemia and Lymphoma 5:1-10.

5.       TUSC3 Loss Alters the ER Stress Response and Accelerates Prostate Cancer Growth in vivo.  Horak P, Tomasich E, Vanhara P, Kratochvilova K, Anees M, Marhold M, Lemberger C, Gerschpacher M, Horvat R, Sibilia M, Pils D, Krainer M (2014) Scientific Reports 4:3739.

6.       UNHCR Nutrition Survey in Afghan Refugee Villages of Pakistan (2014) A collaborative project of SoSec and UNHCR.

7.       Loss of the oligosaccharyl transferase subunit TUSC3 promotes proliferation and migration of ovarian cancer cells. Vaňhara P, Horak P, Pils D, Anees M, Petz M, Gregor W, Zeillinger R, Krainer M (2013) International Journal of Oncology 42(4):1383-9.

8.       Methylation status of TUSC3 is a prognostic factor in ovarian cancer. Pils D, Horak P, Vanhara P, Anees M, Petz M, Alfanz A, Gugerell A, Wittinger M, Gleiss A, Auner V, Cacsire-castillo D, Zeillinger R, Ioana Braicu E,  Sehouli J, Krainer M (2013) Cancer 119(5):946-54.

9.       Education and Training in Transfusion Medicine: A Case of Pakistan. Zaheer HA, Waheed U, Anees M (2013) SAARC Journal of Human Resource Development, ISSN 1816-4366, 9(1)101-107.

10.       Study of the effect of 26RF- and 43RF-amides on Testosterone and Prolactin secretion in the adult male rhesus monkey (Macaca mulatta). Wahab F, Salahuddin H, Anees M, Leprince J, Vaudry H, Tena-Sempere M, Shahab M (2012) Peptides 36(1):23-8.

11.   Human Development in South Asia 2012 Governance for People’s Empowerment. Anees M, Khan RW (2012) SAARC Journal of Human Resource Development, ISSN 1816-4366, 8(1):119-125.

12.   Nutrition Baseline Survey in 11 Districts of KPK and Balochistan (2012) A collaborative project of SoSec, UNICEF, WHO, WFP and AusAID along with Provincial Health Ministries.

13.   hVp37A status determines prognosis and cetuximab sensitivity in ovarian cancer. Wittinger M, Vanhara P, El-Gazzar A, Brenner B, Pils D, Anees M, Grunt TW, Sibilia M, Holcmann M, Horvat R, Schemper M, Zeillinger R, Schoefer C, Dolznig H, Horak P, Krainer M (2011) Clinical Cancer Research 17(24):7816-27.

14.   Recurrence free survival in prostate cancer is related to increased stromal TRAIL expression. Anees M, Horak P, El-Gazzar A, Susani M, Heinze G, Perco P, Pangerl T, Loda M, Lis R, Krainer M, Oh WK (2011) Cancer 117(6):1172-82.

15.   Natural Immunity Enhances the Activity of a DR5 Agonistic Antibody and Carboplatin in the Treatment of Ovarian Cancer. El-Gazzar A, Perco P, Eckelhart E, Anees M, Sexl V, Mayer B, Liu Y, Mikulits W, Horvat R, Pangerl T, Zheng D, Krainer M (2010) Molecular Cancer Therapeutics 9(4):1007-18.

16.   The role of c-FLIPL in ovarian cancer: Chaperoning tumor cells from immunosurveillance and increasing their invasive potential. El-Gazzar A, Wittinger M, Perco P, Anees M, Horvat R, Mikulits W, Grunt TW, Mayer B, Krainer M (2010) Gynecologic Oncology 117(3):451-9.

17.   Dietary Assessment with Reference to Iron Fortified Wheat Flour among Child Bearing Age Women in Manshera –NWFP, Pakistan (2006) World Food Program.


  1. Syphilis and HIV/AIDS among High Risk Groups: A Cross-Sectional Study from Rawalpindi, Pakistan. Raza H, Waheed U, Anees M. 5th Annual Public Health Conference, Health Services Academy, Islamabad, Pakistan. December 11-12, 2014.
  2. National Food Safety Scenario and Strategies for Improvement. Anis RA, Aurangzeb, Anjum F, Anees M. International Congress, University of Agriculture Faisalabad, Pakistan. October 14-16, 2013.
  3. Anomalies of TRAIL Pathway in MALT Lymphoma. Anees M, Horak P, Schiefer AI, Perco P, Müllauer L, Streubel B, Raderer M, Krainer M. International Conference on the Applications of Molecular Biology in Medicine and Agriculture, Islamabad, Pakistan, August 20-22, 2013, abstract # 61.
  4. Loss of death receptor 5 expression in plasmacytic MALT Lymphoma is a common event and is associated with genetic aberrations. Anees M, Horak P, Müllauer L, Streubel B, Raderer M, Krainer M. 102nd Annual meeting of the AACR, Orlando, Florida, USA, April 2–6, 2011, abstract # 4777.
  5. Genetic anomalies in MALT Lymphoma are associated with the loss of death receptor5
    Anees M, Horak P, Müllauer L, Streubel B, Raderer M, Krainer M. 7th YSA PhD Symposium, Medical University of Vienna, Vienna, Austria, June 15–16, 2011, abstract # P06.
  6. The impact of tumor-infiltrating natural killer cells on ovarian cancer progression
    El-gazzar A, Eckelhart E, Perco P, Anees M, Horvat R, Sexl V, Krainer M
    . 102nd Annual meeting of the AACR, Orlando, Florida, USA, April 2–6, 2011, abstract # 3661.
  7. ‘TRAIL’ to Tumor Immune Surveillance. Anees M. International workshop on Advances in Molecular and Cancer Biology, Brno, Czech Republic, November 11-12, 2010, abstract # 01.
  8. TRAIL in tumor microenvironment influences prostate cancer survival. Anees M, Horak P, El-GazzarA, Pangerl T, Susani M, Oh W, Krainer M. 5th PhD Symposium, Medical University of Vienna, Vienna, Austria, June 17–19, 2009, abstract # P04.
  9. Characterization of the TRAIL pathway in a syngenic mouse model of ovarian cancer
    El-gazzar A, Anees M, Horvat R, Mayer B, Krainer M. 100th Annual meeting of the AACR, Denver, Colorado, USA, April 18–22, 2009, abstract # 5128.
  10. Combination of DR5 agonistic antibody and chemotherapy eliminates ovarian cancer in mice. El-Gazzar A, Perco P, Eckelhart E, Anees M, Sexl V, Mayer B, Mikulits W, Krainer M. 5th PhD Symposium, Medical University of Vienna, Vienna, Austria, June 17–19, 2009, abstract P20.
  11. Evidence that evolutionary conserved RF amide neuropeptides stimulate prolactin secretion in the adult male rhesus monkey (Macacamulatta). Salahuddin H, Wahab F, Anees M, Leprince J, Vaudry H, Tena-Sempere M, Shahab M. 1st South Asian Conference of Physiological Societies & 11th Biennial Conference of Pakistan Physiological Society on “Physiology Updates – Trends, Opportunities & Challenges”, Islamabad, Pakistan, November 10-12, 2008.
  12. Kisspeptin does not directly stimulate testosterone secretion in the male rhesus monkey
    Irfan S, Anees M, Zaman W, Shahab M. International Symposium on Endocrinology and Reproductive Sciences, Lahore University of Health Sciences, Lahore, Pakistan, February 13-14, 2007.

1. To Elucidate the Expression of TRAIL Pathway Components in Various Cancer Types

2. To Study the Interplay between Death and Decoy Receptors in Human Cancers

3. Current Antimicrobial Susceptibility Patterns of Escherichia coli species causing Urinary Tract Infection



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