Back
 
Name: Dr. Bushra Mirza
Designation: Professor and Chairperson
Department: Biochemistry (BMB)


Qualifications:

Education:-

March-Nov.     University of North Carolina USA. Post-doc. Project:- Map based cloning 1996                of the Enhancer of gene silencing 1 locus which enhances the silencing of                         a foreign gene in  Arabidopsis. Supervisor:- Dr. Sarah Grant.

1992-96           University of Cambridge, England. Ph.D. in Plant Molecular Biology. Project :-Gene inactivation in transgenic Arabidopsis. Supervisor :- Dr. I. Furner.

1990-92           Quaid-i-Azam University, Pakistan. M.Phil in Genetics. Grade A and 1st position. Project:- Cytogenetical effects of a single treatment of seedlings with 5- azacytidine in selected crops. Supervisor :- Prof. Dr. A.S. Qureshi.

1988-90           Quaid-i-Azam University, Pakistan. M.Sc. in Biological Sciences. GradeA and 1st position.

1985-87           Punjab University, Pakistan. B.Sc  Division 1.

 



Phone: +92-51 9064-3007
Email: bushramirza@qau.edu.pk
Status: On Job
Other Weblink:

View Resume

Research Interests Publications Conferences Research Projects

Plant Molecular Biology and Biochemistry

Genetic transformation of plants

Biological activity of natural and synthetic compounds

1.      N. Safdar, A. Yasmeen and B. Mirza (2011)An insight into functional genomics of transgenic lines of tomato cv Rio Grande harbouring yeast halotolerance genes Plant Biology doi:10.1111/j.1438-8677.2010.00412.x

2.      Saba Irshad, Abdul Mannan and Bushra Mirza (2011) Antimalarial activity of three Pakistani plants. Pakistan Journal of Pharmaceutical Sciences. 24(4):589-591.

3.      G. bibi, Ihsan-ul-Haq, N. Ullah, A. Mannan and B. Mirza (2011) Antitumor, cytotoxic and antioxidant potential of Aster thomsonii extracts. African Journal of Pharmacy and Pharmacology. Vol 5(2,) pp. 252-258.

4.      Haroon Ahmed, Bushra Mirza, Qasim Khan, Waseem Safdar and Mazhar Qayyum (2011) Seroprevalence of hypodermosis (Hypoderma lineatum) in the cattle of potohar region, Pakistan. International Journal of Cell and Molecular Biology 2(2):497-510.

5.      Rehan Naeem, Lynn Dahleen and Bushra Mirza (2011) Genetic differentiation and geographical Relationship of Asian barley landraces using SSRs. Genetics and Molecular Biology 34: 2, 268-273

6.      Zaheer, M, Shah A, Akhter Z , Qureshi R , Mirza B , Tauseef M, Bolte M (2011) Synthesis, characterization, electrochemistry and evaluation of biological activities of some ferrocenyl Schiff bases. Applied Organometalic Chemistry.1 : 61-69                

7.      Hussain A , Mannan A , Zubair H, Mirza B  (2010). Purification and Characterization of Alkaline Proteases from Aspergillus terreus. Journal of the Chemical Society of Pakistan. 32: (4): 497-504

8.      Abdul Mannan, Ibrar Ahmed, Waheed Arshad, Muhammad F Asim, Rizwana A Qureshi, Izhar Hussain and Bushra Mirza (2010) Survey of artemisinin production by diverse Artemisia species in northern Pakistan. Malaria Journal 9:310 doi: 10.1186/1475-2875-9-31.

9.      Muhammad Zia, Bushra Mirza, Salman Akbar Malik and Muhammad Fayyaz Chaudhary (2010) Expression of rol genes in transgenic soybean (Glycine max L.) leads to changes in plant phenotype, leaf morphology, and flowering time. Plant Cell Tiss Organ Cult. 103:227–236

10.  Mukhtiar Hussain, Muhammad Hanif, Muhammad Sheeraz Ahmad, Saqib Ali and Bushra Mirza (2010) Structure Elucidation and Inhibitory Effects of Self Assembled Organotin (IV) Esters of p-tolyl Acetic Acid on Bacterial, Fungal, Brine Shrimps and Potato tumor cells. Drug and Chemical Toxicology 33(2): 183-192

11.   M. Hussain, M. Hanif, S. Ali, S. Shahzadi, M.S. Ahmad, B. Mirza and H.S. Evans (2010) In Vitro Antitomor and Antibacterial Assay of Organotin (IV) Complexes of 2,3-Methylenedioxybenzoic Acid: X-Ray Structure of [(C2H 5)2Sn(C8H5O4)2]. Journal of the Iranian Chemical Society 7(1):155-163.

12.   Muhammad Hanif, Mukhtiar Hussain, Saqib Ali, Moazzam H. Bhatti, Muhammad Sheeraz Ahmed, Bushra Mirza and Helen Stoeckli-Evans (2010) In vitro biological studies and structural elucidation of organotin(IV) derivatives of 6-nitropiperonylic acid: Crystal structure of {[(CH2O2C6H2(o-NO2)COO)SnBu2]2O}2. Polyhedron 29:613-619

13.  Muhammad Adeel Saeed, Muhammad Khawar Rauf, Imtiaz-ud-din, Amin Badshajh, Muhammad Zaeem Akhtar and Busrha Mirza (2010) Some bioactive organotin (IV) derivatives with 3,4-dichlorophenylacetic acid: synthesis, spectroscopic properties and X-ray structure of [Sn4(C4H9)8(OOCCH2C6H3Cl204O2]. Turk J Chem 33:109-118.

14.  Abdual Mannan, Tooba Noor Syed and Bushra Mirza (2009) Factor affecting Agrobacterium tumefaciens mediated transformation of Artemisia absinthium L. Pakistan Journal of Botany 41(6): 3239-3246.

15.  Nighat Fatima, Muhammad Zia, Riaz-ur-Rehaman, Zarrin Fatima Rizvi, Safia Ahmad, Bushra Mirza and M. Fayyaz Chaudhary (2009) Biological activities of Rumex dentatus L: Evaluation if methanol and hexane extracts. African Journal of Biotechnology 8(24): 6945-6950.

16.  Ateeq-ur-Rehman, Abdul Mannan, Samia Inayatullah, M. Zaeem Akhtar, Mazhar Qayyum and Bushra Mirza (2009) Biological evaluation of wild thyme (Thymus serphllum). Pharmaceutical Biology 47 (7):628-633.

17.  Nyla Jabeen Bushra Mirza, Zubeda Chaudhary, Hamid Rashid and Muhammad Gulfraz (2009) Study of factors affecting Agrobacterium mediated gene transformation in tomato (Lycopersicon esculentum Mill.) CV. Riogrande using rice chitinase (CHT-3) gene Pakistan Journal of Botany 41(5): 2605-2614.

18. 

19.  Saqib Ali, Ihsan-ul-Haq and Bushra Mirza (2009) Interaction of Naproxen with Transition Metals: Synthesis, Characterization, Anti-inflammatory Activity and Kinetic Studies. Journal of Coordination Chemistry 62(21): 3463-3470.

20.  Uzma Habib, Amin Badshah, Ulrich Florke, Rizwana Aleem Qureshi, Bushra Mirza, Nazar-ul-Islam, Azeem Khan. Synthesis and structural characterization of (2,4-Diamino-5-(3’, 4’, 5’-Trimethoxy benzyle) Pyrimidine copper(II) Complex. Journal of Chemistry crystallography. 703-734.

21.   Mukhtiar Hussain, Adnan Siddique, Muhammad Sheeraz Ahmad, Muhammad Hanif, Saqib Ali and Bushra Mirza (2009) Dimethyltin(IV) Derivatives of Biologically Potent Substituted Phenylacrylic Acids; Synthesis, Chemical Characterization and Inhibitory Effects on Agrobacterium Tumefaciens Cells. Chemical Biology & Drug Design 74: 183-189.

22.  Uzma Habib, Amin Badshah, Ulrich Fkrke, Rizwana Aleem Qureshi, Bushra Mirza, Nazar-ul-Islam and Azeem Khan (2009) Synthesis of (2,4-Diamino-5-(3’, 4’,5’-trimethoxybemzyl) Pyrimidine) Copper (II) Complex at 20-25° C and its structural characterization. J. Chem. Crystallogr. 39:607-611.

23.  Mukhtiar Hussain, Muhammad Hanif Saqib Ali, Saira Shahzadi, Muhammad Sheeraz Ahmad, Bushra Mirza and Helen S. Evans (2009) Synthesis And Coordination Chemistry Of Organotin(IV) Complexes of 2,3-Methylenedioxyphenylpropenoic Acid. Journal of Coordination Chemistry 62 (13) 2229-2238.

24.  Ibrar Ahmad, Madiha Islam, Abdul Mannan, Rehan Naeem and Bushra Mirza (2009) Optimization of conditions for assessment of genetic diversity in barley (Hordium vulgare L.) using microsettelite markers. Barley Genetic Newsletter 39:5-12.

25.  Ibrar Ahmed, Madiha Islam, Waheed Arshad, Abdul Mannan, Wasim Ahmad and Bushra Mirza (2009) High quality plant DNA extraction, suitable for PCR; is it still a problem? Journal of Applied Genetics 50 (2):105-107.

26.  Haq Nawaz, Zareen Akhter, Sumaira Yameen, Humaria M. Siddiqi, Bushra Mirza and Arshia Rifat (2009) Synthesis and biological evaluations of some Schiff-base esters of ferrocenyl aniline and simple aniline. Journal of Organometallic Chemistry 694: 2198-2203.

27.  Abida Yasmeen, Bushra Mirza, Samia Inayatullah, Naila Safdar, Maryam Jamil and M. Fayyaz Choudhry (2009) In Planta transformation of tomato. Plant Molecular Biology Reporter 27 (1) 20-28.

28.  Muhammad S Ahmad, Bushra Mirza, Mukhtiar Hussain, Muhammad Hanif, Saqib Ali, Michael J Walsh, Francis L Martin (2008) ATR-FTR spectroscopy detects alterations induced by organotin(IV) carboxylates in MCF-7 cells at sub-cytotxic/-genotoxic concentrations. PMC Biophysics 1:3 doi:10.1186/1757-5036-1-3.

29.  Abdual Mannan, Nazia Shaheen, Waheed Arshad, Rizwana Aleem Qureshi, Muhammad Zia and Bushra Mirza (2008) Hairy roots induction and artemisinin in Artemisia dubia and Artemisia indica. African Journal of Biotechnology 7 (18): 3288-3292.

30.  Aamir Saeed, Sabah Zaman, Maryam Jamil and Bushra Mirza (2008) Synthesis and antifungal activity of some novel N-(4-Phenyl-3-aroylthiazol-2(3H)-ylidene) substituted benzamides. Turkish Journal of Chemistry 32: 585-592.

31.  M. Khawar Rauf, M. Adeel Saeed, Imtiaz-ud-Din, M. Bolte, A Badshsah, and Bushra Mirza (2008) Synthesis, characterization and biological activities of some new Organotin (IV) derivatives: Crystal structure of [Sn Ph3)(OOCC6H4OH)] and [(SnMe3)2 (OOC)2C6Cl4 (DMSO)2]. Journal of Organometallic Chemistry 693 (18): 3043-3048.

32.  Farzana Latif Ansari, Fatima Iftikhar, Ihsan-ul-Haq, Bushra Mirza, Mohammad Baseer and Umer Rashid (2008) Solid-phase synthesis and biological evaluation of a parallel library of 2,3-dihydro-1,5-benzothiazepines. Bioorganic & Medicinal Chemistry 16(16): 7691-7697.

33.  M. Hasan, A.J. Khan, S. Khan, A.H. Shah, A.R. Khan and Bushra Mirza (2008) Transformation of tomato (Lycopersicon esculentum Mill.) with Arabidopsis early flowering gene Apetalai (API) through Agrobacterium infiltration of ripened fruits. Pakistan Journal of Botany 40 (1): 161-173.

34.  M. Sheeraz Ahmed, Mukhtiar Hussain, Mohammad Hanif, Saqib Ali,  Mazhar Qayyum and Bushra Mirza (2008) Di- and Triorganotin(IV) esters of 3, 4-Methylenedioxycinnamic Acid: Synthesis, Spectroscopic characterization and Biological Screening of antimicrobial, cytotoxic and antitumor activities. Chem Biol Drug Des 71: 568-576.

35.  Muhammad Zareef, Rashid Iqbal, Bushra Mirza, Khalid M. Khan, Abdul Manan, Faheem Asim and Sher W. Khan (2008) Synthesis and Antimicrobial Activity of some derivatives of acylhydrazine including novel benzenediazasulfonamides. ARKIVOC (ii) 141-152.

36.  Ian Funer, Louise Ellis, Saleha Bahkt, Bushra Mirza and Mazhar Sheikh (2008) The CAUT lines; a novel resource for studies of cell autonomy in Arabidopsis. The Plant Journal. 53 (4):645-660.

37.  A. Mannan, N. Shaheen, A. Rehman, W. Arshad, M. Zia and B. Mirza (2007) Production and release of allelopathic compounds by Artemisia hairy root cultures.  Allelopathy Journal. 20(20): 379-386.

38.  Bushra Mirza, Mohammad Shoaib, Munawar Ahmad, Yong- Bi Fu  (2007) Genetic diversity in Pakistani populations of Avena fatua revealed by seed storage protein polymorphism. Communications in Biometry and Crop Sicence. 2: 41-48.

39.  Muhammad Sheeraz Ahmed, Mukhtiar Hussain, Mohammad Hanif, Saqib Ali, and Bushra Mirza (2007) Synthesis, chemical characterization and biological screening for Antitumor and cytotoxocity of Organotin (IV) derivatives of 3,4-Methylenedioxy 6-nitrophenylpropenic acid. Molecules 12: 2348-2363.

40.  Ahsan Hussain, Muhammad Zia and Bushra Mirza (2007) Cytotoxic and Antitumor potential of Fagonia cretica L. Turkish Journal of Biology. 31: 19-24.

41.  Ahsan Ullah, Farzana Latif Ansari, Ihsan-ul-Haq, Samina Nazir and Bushra Mirza (2007) Combinatorial Synthesis and Antitumour Studies on an Aryl and Heteroaryl Chalcone Library using Positional Scanning Method.  Chemistry and Biodiversity (Switzerland) 4: 203-214.

42.  Samia Inayatullah, Rukhsana Irum, Ateeq-ur-Rehman, M. Fayyaz Chaudhary and Bushra Mirza (2007) Biological Evaluation of Some Selected Plant Species of Pakistan. Pharmaceutical Biology. 45: 397-403.

43.  Mohammad Hanif, Mukhtiar Hussain, Saqib Ali, Moazzam H. Bhatti, M. Sheeraz Ahmed, Bushra Mirza, Helen S. Evans (2007) Synthesis, spectroscopic investigations, crystal structures and biological screening of the organotin (iv) derivatives of peperonylic acid. Turkish Journal of Chemistry 31: 349-361.

44.  Farkhanda Shaheen, Amin Badshah, Marcel Gielen, Michal Duesk, Karla Fejfarova, Dick de Vos and Bushra Mirza (2007) Synthesis, characterization, antibacterial and cytotoxicity activity of new Palladium (II) complexes with Dithiocarbamate ligands. X-ray structure of Bis (dibenzyl-i-s:s’-dithiocarbamato)pd(II) New Palladium(II) Complexes with dithiocarbamate ligands. Journal of Organometallic Chemistry 692: (14) 3019-3026.

45.  Rehan Naeem, Ibrar Ahmed, Rehana Asghar and Bushra Mirza (2006).  Characterization of Hordeum vulgare accessions of Pakistan by Hordein SDS-PAGE. Cereal Research Communications. (Hungary) 34 (4): 1247-1254.

46.  Shawkat Ali and Bushra Mirza (2006) Micropropagation of rough lemon (Citrus jambhiri Lush.): Effect of explants type and hormone concentration. Acta Botanica Croatica. 65 (2): 137-146.

47.  Amna Noor, Zubeda Chaudhry, Hamid Rashid and Bushra Mirza (2006) Evaluation of resitance of rice varieties against bacterial blight caused by Xanthomonas oryzae pv. Oryzae. Pakistan Journal of Botany. 38(1): 193-203.

48.  Nizam-ud-Din, Bushra Mirza, M. Qamar and A. Khabir (2005) Root formation in true potato seed parental lines by IBA application. Pak. J. Agri.Sci., 42(3-4): 29-35.

49.  Farzana Latif Ansari, Samina Nazir, Humaira Noureen and Bushra Mirza (2005) Combinatorial synthesis and antibacterial studies on an indexed chalcone library. Chemistry and Biodiversity (Zurich) 2: 1656-1664.

50.  Nyla Jabeen, Zubeda Chaudhry, Hamid Rashid and Bushra Mirza (2005) Effect of Genotype and explant type on in vitro shoot regeneration of tomato (Lycopersicon esculentum Mill). Pakistan Journal of Botany. 37(4):899-903.

51.  Bushra Mirza (2005) Influence of the nature of the T-DNA insertion region on transgene expression in Arabidopsis thaliana.  Russian Journal of Genetics, 41 (12) 1322-1328.

52.  Amna Noor, Hamid Rashid, Zubeda Chaudhry and Bushra Mirza (2005) High frequency regeneration from scutellum derived calli of basmati rice cv.basmati 385 and super basmati.  Pakistan Journal of Botany. 37(3):673-684

53.  Munawar Ahmad and Bushra Mirza (2005). An efficient protocol for transient transformation of intact fruit and transgene expression in Citrus. Plant Molecular Biology Reporter (Canada) 23: 419a-419k.

54.  Saima Tazeen and Bushra Mirza (2004) Factors affecting Agrobacterium tumefaciens mediated genetic transformation of Vigna radiata L. Wilczek. Pakistan Journal of Botany. 36(4):887-896.

55.  Bushra Mirza (2004) Islamic perspectives on Biotechnology. In: Cross Cultural Biotechnology: Ethical, Legal and Social Issues. (M. Brannigan ed). Rowman & Littlefield Publishers, Inc. Maryland, USA.

56.  Rashida Kanwal, Toqeer Ahmed and Bushra Mirza (2004) Comparative analysis of quality of milk collected from buffalo, cow, goat and sheep of Rawalpindi/Islamabad region in Pakistan. Asian Journal of Plant Sciences. 3(3) 300-305.

57.  Nyla Jabeen and Bushra Mirza (2004) Ethyl Methane Sulfonate induces morphological mutations in Capsicum annuum. International Journal of Agriculture & Biology. 6 (2) 340-345.

58.  Rashida Kanwal, Toqeer Ahmed, I. H. Athar and Bushra Mirza (2002) Comparative analysis of quality of milk collected from Rawalpindi/Islamabad region. Pak. J. Food Sci. 12(1-2) 29-33.

59.  Nyla Jabeen and Bushra Mirza (2002) Ethyl Methane Sulfonate enhances gentic variability in Capsicum annum. Asian Journal of Plant Sciences. 1(4) 425-428.

60.  Nusrat Saba and Bushra Mirza (2002) Ethyl methane sulfonate induced genetic variability in Lycopersicon esculentum. International Journal of Agriculture and Biology 4 (1) 89-92.

61.  Zubeda Chaudary, I. Feroz, Waseem Haider, Hamid Rashid, Bushra Mirza and A. Quraishi (2001) Varietal Response of Lycopersicon esculentum L. to Callogenesis and Regeneration. OnLine Journal of Biological sciences 1 (12) 1138-1140.

62.  Bushra Mirza (2001) Genetic and molecular analysis of transgenic Arabidopsis, using a chlorophyll gene as a marker. Sicience Vision 6(4) 48-55.

63.  Bushra Mirza (2001) Arabidopsis a model system for plant research has been completely sequenced. On line Journal of Biological Sciences 1(4) 298.

64.  Bushra Mirza (2001) Irreversible inactivation of a transgene in Arabidopsis thaliana. Pakistan Journal of Botany 33 (2) 203-209.

65.  Muhammad Ashraf, Afsari Sharif, Bushra Mirza (1995). “Effects of 5-azacytidine on nucleolus in root tip cells of two crops”. The Nucleus 38 (1,2).

66.  Afsari Sharif, Muhammad E. Haq. Bushra Mirza and Muhammad Ashraf (1992) “Ultrastructural Localization of Ag-NOR Stained Proteins in Interphase Nucleolus of Hordeum vulgare”. Journal of Research (Science), 4(1) 1-5.



Quaid-i-Azam University Islamabad, 45320, Pakistan.
Tel: +92-51 9064 0000, Email:webmaster@qau.edu.pk