Humaira Fatima is Assistant Professor of Pharmacognosy in the Department of Pharmacy, Faculty of Biological Sciences at Quaid-I-Azam University. She has a first degree in Pharmacy, an M.Phil. in Pharmaceutical Microbiology, and a PhD in Pharmacognosy. Her research activities are focused on isolation, and characterization of bioactive phytochemicals from ethnomedicinally significant plants. Currently she is working on drug discovery from plants against Leukemia, arthritis, Leishmania, and H. pylori induced gastric carcinoma.
Dr. Humaira Fatima is the author of over 33 research publications. During her 6 years of teaching and research experience, she has supervised 16 M.Phil. students in Pharmacognosy and Pharmaceutical Chemistry and is currently supervising 5 PhD research scholars.
As a Principal Investigator, she is working on the International Foundation for Science (IFS) research grant and a grant through National Research Program for universities (NRPU), HEC, Pakistan (2021-2022). She also served as a Co-Principal Investigator in another NRPU research project on onychomycosis. She has also filed two patent applications, with plans for commercialization upon approval.
Research areas: Natural drug discovery, Ethnobotany, Analytical Chemistry, Phytochemistry
§ Mohsin, S.A., Fatima, H. and Javed, R., 2024. Treatment Strategies Against COVID-19 Using Bioactive Compounds and Plant Secondary Metabolites. In Bioactive Compounds Against SARS-CoV-2 (pp. 125-139). CRC Press.
Publications in WOS & Scopus Indexed Journals
§ Atta, Sania, Anila Sajjad, Humna Sajjad, Humaira Fatima, Muhammad Arslan Ahmad, Mumtaz Cheema and Rabia Javed (2023) Mechanistic insights into Corona viruses and Covid-19: unravelling the possible treatment strategies with emphasis on plant-derived bioactive compounds, Pakistan Journal of Botany
§ Chaudhery, Iqra, Marya Nawaz Malik, Tofeeq Ur Rehman, Humaira Fatima, Asim Ur Rehman, Naveed Ahmed, and Abdelhamid Elaissari (2023), Integrative Validation Method of Rofumilast by Quantifcation and Detection in Lipid Nanoparticles via Reverse Phase HPLC, Chemistry Africa
§ Younatan, Yamema, Muhammad Majid, Abdul Rehman Phull, Muhammad Waleed Baig, Nadeem Irshad, Humaira Fatima, Bakht Nasir, Aroosa Zafar, Abdul Majid, Amna Parveen, and Ihsan-ul Haq (2023),Thymus linearis extracts ameliorate indices of metabolic syndrome in Sprague Dawley rats, Oxidative medicine and cellular longevity
§ Javaid, Maryam, Ihsan-Ul Haq, Humaira Nadeem, Humaira Fatima, Arif-Ullah Khan, and Nadeem Irshad (2023),Design, synthesis and screening of indole acetic acid-based tri-azo moieties as antioxidants, anti-microbial and cytotoxic agents, Frontiers in Pharmacology
§ Atta, Sania, Durdana Waseem, Humaira Fatima, Iffat Naz, Faisal Rasheed, and Nosheen Kanwal (2023),Antibacterial potential and synergistic interaction between natural polyphenolic extracts and synthetic antibiotic on clinical isolates, Saudi Journal of Biological Sciences
§ Atta, Sania, Durdana Waseem, Iffat Naz, Faisal Rasheed, Abdul Rehman Phull, Tofeeq Ur-Rehman, Nadeem Irshad, Parveen Amna, and Humaira Fatima (2023), Polyphenolic characterization and evaluation of multimode antioxidant, cytotoxic, biocompatibility and antimicrobial potential of selected ethno-medicinal plant extracts, Arabian Journal of Chemistry
§ Faiz, Sidra, Durdana Waseem, Ihsan-ul Haq, Malik Mumtaz Taqi, Syeda Aroosa Mohsin, Nadeem Irshad, Abdul Rehman Phull, and Humaira Fatima (2023),Comparative appraisal of in vitro biological profile and in vivo wound healing attributes of bergenin and Bergenia ciliata (Haw.) Sternb, Journal of Ethnopharmacology
§ Dilawar, Naz, Tofeeq Ur-Rehman, Kifayat Ullah Shah, Humaira Fatima, and Aiyeshah Alhodaib (2022),Development and Evaluation of PLGA Nanoparticle-Loaded Organogel for the Transdermal Delivery of Risperidone, Gels
§ Ullah, Kamran Hidayat, Faisal Rasheed, Iffat Naz, Naveed Ul Haq, Humaira Fatima, Nosheen Kanwal, and Tofeeq Ur-Rehman (2022),Chitosan Nanoparticles Loaded Poloxamer 407 Gel for Transungual Delivery of Terbinafine HCl, Pharmaceutics. https://doi.org/10.3390/pharmaceutics14112353
§ Mohsin, Syeda Aroosa, Shazia Shaukat, Marya Nawaz, Tofeeq Ur-Rehman, Nadeem Irshad, Muhammad Majid, Syed Shams Ul Hassan, Simona Gabriela Bungau, and Humaira Fatima (2022),Appraisal of Selected Ethnomedicinal Plants as Alternative Therapies against Onychomycosis: Evaluation of Synergy and Time-kill Kinetics,Frontiers in Pharmacology
§ Sandhu, Marva, Hafiz Muhammad Irfan, Shahid Ali Shah, Madiha Ahmed, Iffat Naz, Muhammad Akram, Humaira Fatima, and Ayesha Shuja Farooq (2022),Friedelin Attenuates Neuronal Dysfunction and Memory Impairment by Inhibition of the Activated JNK/NF-κB Signalling Pathway in Scopolamine-Induced Mice Model of Neurodegeneration, Molecules https://doi.org/10.3390/molecules27144513
§ Nijat Ali, Iffat Naz, Safia Ahmed, Syeda Aroosa Mohsin, Nosheen Kanwal, Humaira Fatima, Shahzad Hussain (2022),Polarity-guided phytochemical extraction, polyphenolic characterization, and multimode biological evaluation of Seriphidium kurramense (Qazilb.) Y. R. Ling, Arabian Journal of Chemistry, ISSN 1878-5352,
§ Kiani, Bushra Hafeez, Fizza Ikram, Humaira Fatima, Aiyeshah Alhodaib, Ihsan-ul Haq, Tofeeq Ur-Rehman, and Iffat Naz (2022),Comparative evaluation of biomedical and phytochemical applications of zinc nanoparticles by using Fagonia cretica extracts,
§ Scientific Reports ,https://doi.org/10.1038/s41598-022-14193-y
§ Saeed, Muhammad, Aqsa Riaz, Azeem Intisar, Mazhar Iqbal Zafar, Humaria Fatima, Haidar Howari, Aiyeshah Alhodaib, and Amir Waseem (2022),Synthesis, characterization, and application of organoclays for adsorptive desulfurization of fuel oil, Scientific Reports,https://www.nature.com/articles/s41598-022-11054-6#citeas
§ Kiani, Bushra Hafeez, Ihsan-ul- Haq, Aiyeshah Alhodaib, Samra Basheer, Humaira Fatima, Iffat Naz, and Tofeeq Ur-Rehman (2022),Comparative Evaluation of Biomedical Applications of Zinc Nanoparticles Synthesized by Using Withania somnifera Plant Extracts, Plants, https://doi.org/10.3390/plants11121525
§ Bashir, Kashaf, Muhammad F.A. Khan, Aiyeshah Alhodaib, Naveed Ahmed, Iffat Naz, Bushra Mirza, Muhammad K. Tipu, and Humaira Fatima (2022),Design and Evaluation of pH-Sensitive Nanoformulation of Bergenin Isolated from Bergenia ciliata, Polymers , https://doi.org/10.3390/polym14091639
§ Murtaza, Ghulam, Muhammad A.A. Maan, Aiyeshah Alhodaib, Muhammad M. Iqbal, Tayyaba Naz, Mazhar I. Zafar, Humaira Fatima, Rashida Parveen, and Iffat Naz (2022), Biogeochemical Behavior of Lead and Nickel as Influenced by Phosphatic Fertilizer Applied to Rice (Oryza sativa L.) Cultivars Grown under City Effluent Irrigation, Water ,https://doi.org/10.3390/w14091319
§ Kazmi, Syeda Tayyaba Batool, Iffat Naz, Syeda Saniya Zahra, Hamna Nasar, Humaira Fatima, and Ayesha Shuja Farooq (2022),Phytochemical analysis and comprehensive evaluation of pharmacological potential of Artemisia brevifolia Wall. ex DC, Saudi Pharmaceutical Journal,https://www.journals.elsevier.com/saudi-pharmaceutical-journal ISSN: 1319-0164
§ Khan, Luqman, Sidra Ghias, Mazhar Iqbal Zafar, Aiyeshah Alhodaib, Humaria Fatima, Tofeeq Ur-Rehman, Amir Waseem, and Haidar Howari (2022),Exploration of microplastic pollution with particular focus on source identification and spatial patterns in riverine water, sediment and fish of the Swat River, Pakistan, RSC Advances ,https://www.rsc.org/journals-books-databases/about-journals/rsc-advances/ISSN: 2046-2069
§ Malik, Marya Nawaz, Ihsan-ul Haq, Humaira Fatima, Madiha Ahmad, Iffat Naz, Bushra Mirza, and Nosheen Kanwal (2022),Bioprospecting Dodonaea viscosa Jacq.; a traditional medicinal plant for antioxidant, cytotoxic, antidiabetic and antimicrobial potential, Arabian Journal of Chemistry,https://www.journals.elsevier.com/arabian-journal-of-chemistry,ISSN: 1878-5352
§ Humaira Fatima, Afeefa Kainat, Fazal Akbar, Zabta Khan Shinwari, and Iffat Naz (2021),Polarity guided extraction, HPLC based phytochemical quantification, and multimode biological evaluation of Otostegia limbata (Benth.) Boiss, Arabian Journal of Chemistry, https://www.journals.elsevier.com/arabian-journal-of-chemistry, ISSN: 1878-5352
§ Baig, Muhammad Waleed, Humaira Fatima, Nosheen Akhtar, Hidayat Hussain, Mohammad K. Okla, Abdulrahman Al-Hashimi, Wahidah H. Al-Qahtani, Hamada AbdElgawad, and Ihsan-ul Haq (2021),Anti-Inflammatory Potential of Daturaolone from Datura innoxia Mill.: In Silico, In Vitro and In Vivo Studies, Pharmaceuticals ISSN 1424-8247 https://www.mdpi.com/journal/pharmaceuticals
§ Javed, Rabia, Farwa Rais, Humaira Fatima, Ihsan ul Haq, Muhammad Kaleem, Syeda Sohaila Naz, and Qiang Ao (2020),Chitosan encapsulated ZnO nanocomposites: Fabrication, characterization, and functionalization of bio-dental approaches, Materials, Science and Engineering: C,0928-4931,1873-0191
§ Humaira Fatima, Madiha Ahmed, Muhammad Waleed Baig, Muhammad Nawaz Tahir, Tamara P. Kondratyuk, and John M. Pezzuto, Ihsan ul Haq (2020),Cancer Chemopreventive and Cytotoxic Activities of Isowithametelin from Datura innoxia, Revista Brasileira de Farmacognosia, ISSN: 0102-695X
§ Muhammad Zafar Irshad Khan, Syeda Saniya Zahra, Madiha Ahmed, Humaira Fatima, Bushra Mirza, Ihsan-ul Haq & Shafi ullah Khan (2018),Polyphenolic profiling of Ipomoea carnea jacq. by HPLC-DAD and its implications in oxidative stress and cancer, Natural product research, Print ISSN: 1478-6419 online ISSN: 1478-6427. Publisher: Taylor & Francis.
§ Sidra Khalid, Shahzad Hussain, Ali, Muhammad Khalid Tipu, Humaira Fatima, Madiha Ahmed and Tofeeq ur-Rehman (2017),Brassica oleracea var. Italica plenck and Cassia absus L. Extracts reduce oxidative stress, alloxan induced hyperglycemia and indices of diabetic complications, Pakistan Journal of Botany, ISSN NO. 0556-3321,Pakistan Journal of Botany, Botanical Garden, University of Karachi, Pakistan
§ Madiha Ahmed, Humaira Fatima, Muhammad Qasim, Bilquees Gul and Ihsan-ul Haq (2017),Polarity directed optimization of phytochemical and in vitro biological potential of an indigenous folklore: Quercus dilatata lindl. Ex royle, BMC Complementary and Alternative Medicine, Doi: 10.1186/s12906-017-1894-x
§ Bakht Nasir, Madiha Ahmed, Bushra Mirza, Tofeeq ur-Rehman and Humaira Fatima (2017),Pharmacological evaluation of Fumaria indica (hausskn.) Pugsley; a traditionally important medicinal plant, Pakistan Journal of Botany ISSN NO. 0556-3321,Pakistan Journal of Botany, Botanical Garden, University of Karachi, Pakistan
§ Humaira Fatima, Komal Khan, Muhammad Zia, Tofeeq ur-Rehman, Bushra Mirza and Ihsan-ul Haq (2015),Extraction optimization of medicinally important metabolites from Datura innoxia mill.: an in vitro biological and phytochemical investigation, BMC Complementary and Alternative Medicine, doi 10.1186/s12906-015-0891-1
§ Komal Khan, Humaira Fatima, Malik Mumtaz Taqi, Muhammad Zia, Tofeeq ur-Rehman, Bushra Mirza, Ihsan-ul Haq (2015),Phytochemical and in vitro biological evaluation of Artemisia Scoparia waldst. & kit for enhanced extraction of commercially significant bioactive compounds, Journal of Applied Research on Medicinal and Aromatic Plants Http://Dx.Doi.Org/10.1016/J.Jarmap.2015.04.002
§ Fatima Javed, Saqib Ali, Muhammad Wajid shah, Khuram Shahzad Munawar, Saira Shahzadi, Hameedullah, Humaira Fatima, Madiha Ahmed, Saroj K. Sharma, kushal Qanungo (2014),synthesis, characterization, semi empirical study and biological activities of organotin (iv) and transition metal complexes with o-methyl carbonodithioate, Journal of coordination chemistry, http: 00dx.doi.org/10.1080/00958972.2014.947967
§ Bakht Nasir, Humaira Fatima, Madiha Ahmad and Ihsan-ul-Haq (2017),Cannabis: a prehistoric remedy for existing and emerging anticancer therapies, Journal of Exploratory Research in Pharmacology. Doi: 10.14218/jerp.2017.00012
§ Bakht Nasir, Humaira Fatima, Madiha Ahmad and Ihsan-ul-Haq (2014),Recent trends and methods in antimicrobial susceptibility testing of drugs obtained from plant sources, Austin Journal of Microbiology.
§ Appraisal of Secondary Metabolites from Seriphidium kurramense as Therapeutic Leads against Cancer and Arthritis, as Principal investigator from Higher Education Commission Pakistan through NRPU.
§ Isolation of antileishmanial compounds from Datura innoxia, as Principal Investigator-from International foundation for science (IFS).
§ Development and in vitro evaluation of Novel antifungal nail patches against clinical isolates from diabetic onychomycosis patients of Islamabad, as co-principal investigator-Research grant from Higher Education Commission Pakistan through NRPU.