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Bioinformatics at the "National Center
for Bioinformatics" Faculty of Biological Sciences,
Quaid-i-Azam University, Islamabad, Pakistan
Bioinformatics originated as a cross-disciplinary
field as the need for computational solutions to research problems raised
in biomedicine. The field evolved as computation became cheaper and widespread
during the 80s, as the Internet grew during the 90s, and as high-throughput
technologies become common in the 2000s. The use of computational methods
in biomedicine deals with the analysis, storage, manipulation and interpretation
of macromolecules such as DNA, RNA and proteins. The massive quantities
of data generated by genomic research and analysis of this data through
computational tools allow for the interpretation of the hidden information
contents within macromolecules and their roles in the game of life. Conversely,
the wet lab analysis of computationally predicted functionally relevant
motifs/segments of macromolecules further enhances our understanding of
what is going on in cells.
The National Center for Bioinformatics will provide basic and advanced
level research training to young Pakistani scholars in the field of bioinformatics--an
emerging discipline. Our vision to establish programs such as: DNA mapping
and sequencing, string storage and string manipulation: pattern matching
and string alignments: multiple alignment: gene finding: genome comparison:
protein structure prediction: regulatory network analysis: modeling biological
systems: deciphering transcriptomic data generated by high-throughput
experimental technologies.
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